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We turn
seed-stage risk
into Series A-ready
investments

Most funds accept that 60% of their portfolio won't perform. Too often, investors think they're funding growth when they're still funding validation.

2blabs is built to change that ratio — to de-risk deep tech companies between Seed and Series A.

We combine pre-investment analysis with a sector-specific post-investment support — linking capital to milestones.

10 European ecosystems — Pan-European deep tech access 15,000 startups accessible through our network 300+ startups analysed per programme each year <20% mortality after 3 years vs. ~60% market 2.5×–5× valuation uplift within 24–36 months 6 investments completed in the last 12 months

Deal flow is no longer scarce.
Execution readiness is.

AI-driven sourcing has commoditised access to startups. At the same time, competition is pushing valuations earlier, while execution and market readiness remain difficult to assess.

The result: capital is often deployed too early relative to startup maturity.

This is particularly visible between Seed and Series A — where most value is lost.

The real bottleneck is not access.
It is knowing when and what to invest in.

Deep tech investments rarely fail
because of access.

They fail because capital and execution are misaligned.

01

Premature Deployment

Capital deployed before market readiness — startups spend before they can sell.

02

One-Shot Investment

Single lump-sum investment instead of staged deployment aligned to execution milestones.

03

Valuation Mismatch

Valuations driven by competitive pressure rather than actual startup readiness.

04

Sectorial Execution Gap

Execution risk is not addressed post-investment. Without deep, sector-specific execution, portfolio companies are left to navigate critical scale-up challenges alone.

05

No Milestone Alignment

No structured link between capital deployment and verified progress milestones.

Higher portfolio risk Inefficient capital allocation Lower risk-adjusted returns

This is the gap 2B Labs was built to close.

Deep tech isn't one market.

Different sectors. Different execution risks. Same capital challenge.

HealthTech

  • Regulatory & clinical timelines misaligned with capital deployment
  • High cost and long duration of clinical validation phases
  • Complex go-to-market: hospitals, payers, and public health systems
  • Reimbursement uncertainty blocking and delaying revenue
  • Scientific founders with limited commercial execution capacity
Same problem

ClimateTech

  • High capex requirements and strong infrastructure dependency
  • Long industrialisation cycles and extended time-to-market
  • Heavy reliance on industrial and corporate partnerships for pilots
  • Adoption risk driven by cost competitiveness vs. incumbents
  • Exposure to regulation shifts and public policy changes

From investment readiness
to Series A.

A structured de-risking process that helps VC funds determine when to invest, how to structure capital and support execution after investment.

Pre-Investment Analysis Investment Decision & Structuring Post-Investment Support
Know when to invest → Structure how to invest → Execute to scale
Click any step below to explore how it works
Phase 1 Pre-Investment Analysis

Is this company truly ready for investment?

Phase 2 Investment Decision & Structuring

How and when should capital be deployed?

Phase 3 Post-Investment Support

How do we turn capital into execution, traction and Series A readiness?

Click any step above to see how it works.
Phase 1 · Pre-Investment Analysis

01 — Thesis-driven sourcing

Pan-European pipeline across 10 ecosystems, filtered by your investment mandate, sector focus and stage.

Not database noise. Direct access to founders, research ecosystems and specialised deep tech networks.
Phase 1 · Pre-Investment Analysis

02 — Investment Readiness Assessment

We structure each investment across six key dimensions.

01

Technology & Innovation

  • Attractiveness & disruption level
  • Competitive advantage vs existing solutions
  • Minimum marketable product plan
  • TRL maturity & scalability
02

Patentability & Freedom to Operate

  • Patentability of core technology
  • Freedom to Operate confirmed
  • IP ownership structure clear
  • No 3rd party infringement risk
03

Market & GTM Readiness

  • Value proposition validated with customers
  • Market size and growth trajectory
  • Industry validation (corporate interest)
  • Paid pilots or commercial LOIs in place
04

Cap Table & Equity Structure

  • Tech transfer & SHA aligned
  • Dilution runway for 2+ rounds
  • No blocking institutional equity
05

Team, Story & Narrative

  • Founder-market fit & domain expertise
  • Execution track record
  • Investor narrative is compelling & clear
  • VC-ready materials and data room
06

Regulatory & Financial Path

  • Regulatory strategy mapped (CE/FDA/EU)
  • Compliance timeline aligned with GTM
  • Financial forecast & runway
  • Tech roadmap linked to capital milestones
Phase 1 · Pre-Investment Analysis

03 — Investability Report & Execution Plan

Output
  • Investment recommendation: invest now / later / do not invest
  • Key risks and execution gaps
  • Tailored sectorial execution roadmap
  • Milestones and timing
  • Capital deployment strategy
  • Refined investment materials and data room
Phase 2 · Investment Decision & Structuring

04 — VC Selection Committee

Your fund makes the final investment decision — based on the Investment Readiness Assessment, the Investability Report, identified execution gaps, proposed milestones and the capital deployment strategy. The founding team presents in a live pitch and elevator session with our sector experts and your fund. Not a pitch deck alone.

Phase 2 · Investment Decision & Structuring

05 — Milestone-based Investment

Investment can be structured around validated execution milestones — often through staged capital deployment rather than a single upfront investment.

Phase 3 · Post-Investment Support

06 — Public Funding & GTM Definition

Once capital is deployed, 2B Labs stays actively involved to build the foundation for scale.

  • Sector-specific GTM strategy and positioning
  • Business model / pricing validation where relevant
  • Regulatory and market access readiness
  • Public and non-dilutive funding
  • Strategic partnerships and ecosystem access
Phase 3 · Post-Investment Support

07 — Execution

Driving measurable traction and next-round readiness.

  • Commercial traction and customer acquisition
  • Commercial agreements and partnerships
  • International expansion
  • Team and execution strengthening
  • Fundraising / investor readiness
  • Series A preparation

Built around each fund's thesis.
Designed around each sector's reality.

Each 2B Labs programme combines a dedicated investment mandate, pan-European sourcing, sector-specific validation, structured investment and post-investment execution.

Active · Since January 2025

HealthTech Programme

VC Partner6 European HealthTech VCs
Investment per startup€200k guaranteed
Target TRL6–9 · First sales ≤ 2 years
Startups analysed300+

Healthtech Areas of Interest

01
AI-Driven Personalised Health Coaching

Tailored nutritional and lifestyle advice. Enhances patient engagement and outcomes.

02
Remote Patient Monitoring Systems

IoT devices tracking vital signs and health metrics in real-time. Enables continuous data sharing with healthcare providers.

03
Telemedicine Platforms with AI Diagnostics

Advanced AI-driven capabilities for remote consultations. Increases healthcare accessibility and efficiency.

04
Digital Therapeutics

Evidence-based software interventions to prevent, manage, or treat medical conditions. Supplements traditional therapies and promotes proactive health management.

05
Blockchain Technology for Health Data Management

Secure and transparent health record handling. Ensures patient privacy and data integrity.

06
Home Diagnostic Devices

Consumer-friendly tools for early detection of chronic diseases. Integration with digital health records for remote physician review.

07
Behavioural Health and Wellness Apps

AI-driven solutions for managing stress, sleep, and mental health. Tools for cognitive behavioural therapy and mindfulness.

08
Rehabilitation Technologies

Robotics and AI for physical therapy and post-surgery recovery. Virtual reality platforms to enhance patient mobility and adherence to rehabilitation programmes.

09
Nutraceuticals and Functional Foods

AI-driven platforms for personalised supplementation recommendations. Innovative delivery systems for bioactive compounds.

10
Wearable Tech for Geriatric Care

Devices with fall detection and emergency response capabilities. Cognitive monitoring to detect early signs of dementia or Alzheimer's.

11
Augmented Reality (AR) for Medical Training and Patient Education

AR-based simulations for healthcare providers to practice procedures. Interactive tools for educating patients on their conditions and treatments.

300+HealthTech projects reviewed since January 2025. Tap a category to see what we've seen.
Tap a category above to see the kind of projects we've reviewed.
~1B people affected
  • Insomnia treatment — vagus nerve stimulation earbud
  • Telemedicine platform for sleep
  • Mental health chatbot & therapy for Parkinson's
  • Stroke home rehabilitation with VR, EMG, robotics
  • Biochemical triage test for stroke
Hundreds of millions affected
  • At-home physiotherapy
  • Compression therapy monitoring for venous ulcers
450M+ women affected
  • Hot flash relief wearable for menopause
  • Breast self-exam device for early cancer detection
  • Earbuds with vital sign monitoring
  • Body temperature monitoring
  • Middle ear pressure regulation device
  • AI-based skin cancer detection
25% of global adults affected
  • Glucose monitoring — infrared device, needle-free patch, saliva
  • Saliva-based biomarker diagnostics
  • Nutritional guidance platform

What makes it tailored

01
Regulatory pathway built into milestones

CE/MDR, FDA and IVDR strategy mapped and integrated from day one — not as an afterthought. Capital tranches aligned with regulatory checkpoints.

02
Clinical validation aligned with capital

First tranche at TRL 6–7. Second tranche triggered by validated clinical data, paid pilots or commercial LOIs — never by time alone.

03
GTM for health systems, not just markets

Hospital procurement, payer reimbursement and public health navigation built into the commercial support. We know how health systems buy.

04
Scientific-to-commercial transition

We bridge the gap between deep scientific expertise and commercial execution capacity — the most common failure point in HealthTech.

What's included

  • Patient pathway mapping & healthcare system navigation
  • Clinical evidence strategy & validation milestones
  • Regulatory review: CE, MDR, FDA, IVDR
  • Reimbursement strategy (EU HTA, CPT codes)
  • Hospital, payer & KOL introduction network
  • Health data compliance framework (GDPR / HIPAA)
  • Medical affairs & scientific communication
  • Investment readiness for health-focused VCs
Active · Since September 2025

ClimateTech Programme

VC Partner3 European ClimateTech VCs
Investment per startup€500k – €1M guaranteed
Target TRL8–9 · First sales ≤ 1 year
Startups analysed200+

Climatetech Areas of Interest

Energy Transition
  • Long duration batteries, flow batteries and new materials for storage such as sodium
  • Thermal storage for medium and high temperature
  • Optimisation software for renewable energies and P2P energy platforms
  • Renewable energies for high temperature heat production
  • Software for consumption/production optimisation and forecasting
Circular Economy
  • Advanced recycling using AI or chemical processes
  • Waste reuse and valorisation platforms
  • Water management and regeneration solutions
  • Biobased and biodegradable materials
  • Digital traceability for circular products (blockchain, RFID)
  • Software for resource optimisation and reverse logistics
  • CO2 usage in the industry
Industrial Decarbonisation Technologies
  • Mineralisation of CO2 or DAC
  • Upgrading of biogas
  • Production of sustainable fuels
  • Scalable and cost-efficient green hydrogen
  • Biomass production
  • Use of agricultural and industrial waste
  • Modelling and processing for emissions reduction
  • Climate change prediction tools
Low Carbon Economy
  • Carbon Capture, Utilisation and Storage (CCUS)
  • Electrification of industrial processes
  • Green hydrogen production
  • Low-emission alternative materials
  • Energy optimisation using AI
  • Risk prediction and detection tools due to climate change
  • AI systems to optimise resource allocation
200+ClimateTech projects reviewed since July 2025. Tap a category to see what we've seen.
Tap a category above to see the kind of projects we've reviewed.
  • Energy storage technologies
  • Smart grid & energy management
  • Renewable energy generation
  • Waste-to-energy
  • Waste-to-value & waste valorisation
  • Circular materials & sustainable composites
  • Circular energy systems
  • Circular supply chains & resource optimisation
  • CO₂ reduction & avoidance
  • Decarbonised energy systems
  • Carbon removal technologies
  • Sustainable infrastructure & monitoring
  • CCUS — carbon capture, utilisation & storage
  • Hydrogen & e-fuels
  • Low-carbon industrial processes
  • Zero-emission heavy industry & mobility

What makes it tailored

01
Industrial partnership strategy from week one

Tier 1 industrial corporates, utilities and infrastructure players integrated into the programme from the start — not at demo day.

02
Capex-aware capital structuring

Investment structured to bridge the gap between first pilots and commercial deployment, accounting for infrastructure intensity and long development cycles.

03
EU taxonomy & regulatory compliance embedded

CSRD, EU Green Deal alignment and EU taxonomy mapping embedded in the investor narrative — essential for attracting institutional climate capital.

04
Pilot-to-commercial bridge

Commercial agreements and industrial licensing structured to de-risk the scale-up from proof-of-concept to full industrial deployment.

What's included

  • Industrial corporate partner introductions (energy, manufacturing, infrastructure)
  • EU taxonomy & CSRD compliance framework
  • Public funding access (Horizon Europe, EIC, national funds)
  • Technical due diligence for hard-tech & deep-science projects
  • Capex & project finance structuring guidance
  • Regulatory navigation (EU ETS, emissions standards)
  • Industrial pilot design & corporate agreement structuring
  • Investment readiness for climate-focused & impact VCs

Companies we've backed.

Deep tech companies selected through our structured investment process and supported from investment through execution.

HealthTech Programme All backed through our active programme
Click each company to explore its portfolio profile
Digital Health · Medical Device

Ephion Health

A hardware-agnostic AI platform that transforms multimodal data from third-party wearables into clinically validated, patented digital biomarkers — precisely measuring disease progression and response to therapy. Spun off from Eurecat and Hospital Sant Joan de Déu in Barcelona, with first products clinically validated for neuromuscular diseases, frailty and stroke rehabilitation, and CE SaMD IIa certification targeted for 2026.

Visit ephion.health ↗
Diagnostics

DEBIOS

Redefining kidney care through non-invasive diagnostics. Chronic kidney disease is silent and underdiagnosed — fibrosis, its key prognostic factor, still relies on invasive biopsy. DEBIOS' FIBROKIT® is a first-in-class urine-based IVD test that detects and monitors renal fibrosis with biopsy-level precision, based on patented urinary vitronectin and proprietary monoclonal antibodies, validated across 300+ patient samples and more than 30 leading nephrologists.

Visit debiosdx.com ↗
SleepZzone

SleepZzone

The first European SleepTech of its kind. Poor sleep is a silent productivity crisis — costing employers thousands per employee per year — yet no integrated, medical-grade B2B solution existed. SleepZzone is an AI-driven Medical SaaS 360° platform combining clinical assessment, multidisciplinary therapy (doctor, psychologist, physical activity, dentist, nutritionist), gamification and corporate ROI dashboards, delivering an 85% treatment success rate across its network of sleep clinics.

Visit sleepzzone.com ↗
Rehabilitation

QuestPrehab

AI-enabled peri-operative care and patient optimisation, reducing complications and costs in cancer and surgical care. Traditional prehab requires repeated hospital visits most patients can't sustain — QuestPrehab delivers five AI-supervised care modules (exercise, nutrition, mental preparation, respiratory exercises and patient education) digitally, from referral through to post-op support, already used to optimise over 2,800 patients while cutting 90-day readmissions by half.

Visit questprehab.com ↗
Mental Health · Digital Therapeutics

WakeZ

The first Digital Molecule for Depression. WakeZ pairs an Apple Watch with a clinically validated, patented haptic protocol that gently reduces REM sleep to ease depressive symptoms — no medication, no side effects. Built on peer-reviewed sleep science, it has shown a 33.8% reduction in patient-reported depressive symptoms across double-blind clinical trials.

Visit wakez.ai ↗
HealthTech · Patient Engagement

Serena Labs

The preventive intelligence layer for healthcare. Serena Labs' AI engine turns everyday interactions into early health signals, then acts on them — steering people through acquisition, engagement and retention journeys for insurers and pharma. Proven at scale in Latin America, including a 6× conversion lift for the region's largest health insurer, and now expanding into Spain and the rest of Europe via the Barcelona Health Hub.

Visit serenalabs.io ↗

Partners that already trust us

3xP Global
Afi Ventures
BuenaVista Equity Partners
CRB Healthtech
Suma Capital
Inclimo
Inveniam
S2 XPEED
La Salle Technova Barcelona
F319

We turn Deep Tech opportunities into investable companies.
Sourcing. Readiness. Execution.

10countries
Pan-European access to deep tech ecosystems.
15,000
Deep tech startups accessible through our network.
300+
Startups analysed per programme each year.
6
Startups invested in during the last 12 months.
<20%
Portfolio mortality after 3 years vs. ~60% market.
2.5×–5×
Valuation uplift within 24–36 months at the next round.

Deep tech operators
turned investment enablers.

Our team combines deep tech venture building, technology transfer, investment readiness, market acceleration and hands-on company execution.

Oscar Sala

Oscar Sala

CEO & Deep Tech Venturing Partner

Former Managing Director of The Collider, the European technology transfer programme. Launched 20+ deep tech spin-offs in four years across HealthTech, ClimateTech and FoodTech, while overseeing 400+ deep tech projects annually.

20+ spin-offs launched
400+ projects/year
European deep tech ecosystem experience
Noemí Artal

Noemí Artal

Marketing & Communication

Journalist specialising in strategic marketing and communications for innovation and technology. Works with companies to translate complex technologies into clear market positioning, commercial narratives and investor communication.

Journalist · Strategic marketing & communications
Turns complex tech into clear market narratives
Drives brand positioning & thought leadership
Pancho Sala Esteve

Pancho Sala Esteve

Programme Executive

Supports the end-to-end execution of 2B Labs programmes, coordinating startups, partners, investment processes and day-to-day programme operations.

Coordinates programme activities & daily operations
Key point of contact for startups & partners
Drives project delivery & event execution

Looking to improve how your fund invests in deep tech? Let's talk.